abstract：:Neuropathic pain treatment remains unsatisfactory despite a substantial increase in the number of trials. This EFNS Task Force aimed at evaluating the existing evidence about the pharmacological treatment of neuropathic pain. Studies were identified using first the Cochrane Database then Medline. Trials were classifie...

journal_title：European journal of neurology

authors： Attal N,Cruccu G,Haanpää M,Hansson P,Jensen TS,Nurmikko T,Sampaio C,Sindrup S,Wiffen P,EFNS Task Force.

更新日期：2006-11-01 00:00:00

abstract：:Complex painful reflex syndrome is sometimes described in the chronic phase of stroke. Acute autonomic dysfunction (AAD), which is occasionally present in cases of acute stroke, has not been studied prospectively. The aim of the study was to investigate AAD on the hemibody contralateral to the lesion in the acute phas...

journal_title：European journal of neurology

authors： Diserens K,Vuadens P,Michel P,Reichhart M,Herrmann FR,Arnold P,Bogousslavsky J,Ghika J

更新日期：2006-11-01 00:00:00

abstract：:Four hundred and sixty records of patients with primary torsion dystonia (296 women and 164 men) were evaluated. The mean age at disease onset was 48.3 +/- 17.7 years; 13 patients carried the DYT1 CAG deletion. The distribution of age at onset was represented by a bi-modal curve, with a nadir at 21 year separating ear...

journal_title：European journal of neurology

authors： Elia AE,Filippini G,Bentivoglio AR,Fasano A,Ialongo T,Albanese A

更新日期：2006-10-01 00:00:00

abstract：:We performed a placebo-controlled cross-over trial of riluzole (100 mg b.i.d.) in 10 patients with probable multiple system atrophy (MSA) administering riluzole and placebo for 4 weeks each with a 4-week washout period. Outcome measures evaluated short-term anti-Parkinsonian effects using the Unified Parkinson's Disea...

journal_title：European journal of neurology

authors： Seppi K,Peralta C,Diem-Zangerl A,Puschban Z,Mueller J,Poewe W,Wenning GK

更新日期：2006-10-01 00:00:00

abstract：:We evaluated the putative factors for the onset of Guillain-Barré syndrome (GBS) in Harbin, China by a case-control study based on the information from GBS patients identified from a population-based incidence survey, which is the first study of this kind in China. Sixty-nine GBS patients were identified during a 1-ye...

journal_title：European journal of neurology

authors： Cheng Q,Wang DS,Jiang GX,Han H,Zhang Y,Wang WZ,Fredrikson S

更新日期：2006-09-01 00:00:00

abstract：:Post-marketing surveillance studies are needed to assess the long-term safety, compliance and clinical efficacy of interferon beta-1a (IFNbeta-1a) therapy in multiple sclerosis (MS) patients. The goals of this study were to (i) assess the safety, compliance and clinical efficacy of long-term intramuscular (i.m.) IFNbe...

journal_title：European journal of neurology

authors： Coppola G,Lanzillo R,Florio C,Orefice G,Vivo P,Ascione S,Schiavone V,Pagano A,Vacca G,De Michele G,Morra VB

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Paraprotein-associated neuropathies have heterogeneous clinical, neurophysiological, neuropathological and haematological features. Objectives. To prepare evidence-based and consensus guidelines on the clinical management of patients with both a demyelinating neuropathy and a paraprotein (paraproteinaemic de...

journal_title：European journal of neurology

authors： European Federation of Neurological Societies.,Peripheral Nerve Society.,Hadden RD,Nobile-Orazio E,Sommer C,Hahn A,Illa I,Morra E,Pollard J,Hughes RA,Bouche P,Cornblath D,Evers E,Koski CL,Léger JM,Van den Bergh P,van Door

更新日期：2006-08-01 00:00:00

abstract：:Hereditary spastic paraparesis (HSP) is a heterogeneous group of neurodegenerative disorders with progressive lower limb spasticity, categorized into pure (p-HSP) and complicated forms (c-HSP). The purpose of this study was to evaluate if brain volumes in HSP were altered compared with a control population. Brain volu...

journal_title：European journal of neurology

authors： Kassubek J,Sperfeld AD,Baumgartner A,Huppertz HJ,Riecker A,Juengling FD

更新日期：2006-08-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic and potentially highly disabling disorder with considerable social impact and economic consequences. It is the major cause of non-traumatic disability in young adults. The social costs associated with MS are high because of its long duration, the early loss of productivity, the nee...

journal_title：European journal of neurology

authors： Pugliatti M,Rosati G,Carton H,Riise T,Drulovic J,Vécsei L,Milanov I

更新日期：2006-07-01 00:00:00

abstract：:Spontaneous intracranial hypotension (SIH) is characterized by orthostatic headache and the cause is usually cerebrospinal fluid leaks in spine level. Most patients with SIH have a benign course. Epidural blood patch (EBP) is the treatment of choice when initial conservative managements are ineffective. We reported a ...

journal_title：European journal of neurology

authors： Tsui H,Wu S,Kuo H,Chen C

更新日期：2006-07-01 00:00:00

abstract：:Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients' quality of life. To give evidence-based or expert recommendations for the different drug treatment procedures of the different migraine syndromes based on a literature search and an consensus in an expert panel....

journal_title：European journal of neurology

authors： Members of the task force:.,Evers S,Afra J,Frese A,Goadsby PJ,Linde M,May A,Sándor PS

更新日期：2006-06-01 00:00:00

abstract：:The Australian Pregnancy Registry, affiliated European Register of Antiepileptic drugs in Pregnancy (EURAP), recruits informed consenting women with epilepsy on treatment with antiepileptic drugs (AEDs), those untreated, and women on AEDs for other indications. Enrolment is considered prospective if it has occurred be...

journal_title：European journal of neurology

authors： Vajda FJ,Hitchcock A,Graham J,Solinas C,O'Brien TJ,Lander CM,Eadie MJ

更新日期：2006-06-01 00:00:00

abstract：:An evaluation of general antiepileptic treatment patterns and utilization of particular drugs was carried out based on the prevalence study of adult active epilepsy in a sample of the Estonian population. The antiepileptic drugs (AEDs) used, and their doses were recorded and compared with clinical characteristics. Nin...

journal_title：European journal of neurology

authors： Oun A,Haldre S,Mägi M

更新日期：2006-05-01 00:00:00

abstract：:Abnormal neuronal intermediate filament (IF) inclusions immunopositive for the type IV IF alpha-internexin have been identified as the pathological hallmark of neuronal intermediate filament inclusion disease (NIFID). We studied the topography of these inclusions in the frontal and temporal lobe in 68 areas from 10 ca...

journal_title：European journal of neurology

authors： Armstrong RA,Cairns NJ

更新日期：2006-05-01 00:00:00

abstract：:The present review of epidemiologic studies on migraine and headache in Europe is part of a larger initiative by the European Brain Council to estimate the costs incurred because of brain disorders. Summarizing the data on 1-year prevalence, the proportion of adults in Europe reporting headache was 51%, migraine 14%, ...

journal_title：European journal of neurology

authors： Stovner LJ,Zwart JA,Hagen K,Terwindt GM,Pascual J

更新日期：2006-04-01 00:00:00

abstract：:It is not well established whether seizures and epilepsy after an ischaemic stroke increase the disability of patients. Seventy-two patients with delayed seizures after a hemispheric infarct (37 with a single seizure and 35 with epilepsy) were included in the study. The modified Rankin scale was used to compare disabi...

journal_title：European journal of neurology

authors： De Reuck J,Claeys I,Martens S,Vanwalleghem P,Van Maele G,Phlypo R,Hallez H

更新日期：2006-04-01 00:00:00

abstract：:Although migraine is a neurovascular disorder, both scalp tenderness and referred pain have been observed in migraine patients. The present study was carried out to investigate the presence of trigger points eliciting referred pain in 98 migraine patients and in 32 healthy subjects. Trigger points were found in 92 (93...

journal_title：European journal of neurology

authors： Calandre EP,Hidalgo J,García-Leiva JM,Rico-Villademoros F

更新日期：2006-03-01 00:00:00

abstract：:Hypoalbuminemia is associated with increased risk of infections. The aim of this study was to determine if serum albumin level is an independent predictor of nosocomial pneumonia in stroke patients. Data of 705 consecutive ischemic stroke patients admitted within 24 h after stroke onset were analyzed retrospectively. ...

journal_title：European journal of neurology

authors： Dziedzic T,Pera J,Klimkowicz A,Turaj W,Slowik A,Rog TM,Szczudlik A

更新日期：2006-03-01 00:00:00

abstract：:Myelitis is one of the most severe central nervous system complications seen in association with Mycoplasma pneumoniae infections and both acute transverse myelitis (ATM) as well as acute disseminated encephalomyelitis (ADEM) have been observed. We reviewed all available literature on cases of Mycoplasma spp. associat...

journal_title：European journal of neurology

authors： Tsiodras S,Kelesidis T,Kelesidis I,Voumbourakis K,Giamarellou H

更新日期：2006-02-01 00:00:00

abstract：:We evaluated the cerebral hemodynamic features of severe bilateral carotid stenosis by assessing and comparing cerebral vasomotor reactivity (VMR) in the middle cerebral (MCA) and vertebral arteries (VA) by transcranial Doppler and the Diamox (1 g acetazolamide i.v.) test. VMR was evaluated by recording the percentage...

journal_title：European journal of neurology

authors： Gur AY,Bornstein NM

更新日期：2006-02-01 00:00:00

abstract：:In recent years, a number of potential new therapeutic indications of botulinum toxin injections have emerged, amongst which sialorrhea has attracted considerable attention. Based on open-label and controlled studies, botulinum toxin can be used to improve sialorrhea in patients with Parkinson's disease, parkinsonian ...

journal_title：European journal of neurology

authors： Tan EK

更新日期：2006-02-01 00:00:00

abstract：:The aim of the study was to use functional transcranial Doppler to investigate the possibility of revealing different activation patterns during healthy subjects' performance of meaningful and meaningless actions. Mean flow velocity (MFV) changes were recorded in middle cerebral arteries (MCAs) of 26 normal subjects d...

journal_title：European journal of neurology

authors： Matteis M,Federico F,Troisi E,Pasqualetti P,Vernieri F,Caltagirone C,Petrosini L,Silvestrini M

更新日期：2006-01-01 00:00:00

abstract：:Mirror movements (MM), involuntary movements of homologous muscles opposite to unilateral limb activity, decrease in the course of motor development, but may reappear in adults after brain damage. To better characterize this type of acquired MM, grip forces of 36 healthy subjects and 35 patients suffering from focal b...

journal_title：European journal of neurology

authors： Uttner I,Mai N,Esslinger O,Danek A

更新日期：2005-12-01 00:00:00

abstract：:Therapy-induced binding and neutralizing antibodies is a major problem in interferon (IFN)-beta treatment of multiple sclerosis. The objective of this study was to provide guidelines outlining the methods and clinical use of the measurements of binding and neutralizing antibodies. Systematic search of the Medline data...

journal_title：European journal of neurology

authors： Sørensen PS,Deisenhammer F,Duda P,Hohlfeld R,Myhr KM,Palace J,Polman C,Pozzilli C,Ross C,EFNS Task Force on Anti-IFN-beta Antibodies in Multiple Sclerosis.

更新日期：2005-11-01 00:00:00

abstract：:We performed a 2-year population-based study on status epilepticus (SE) in adults in the rural area of Lugo di Romagna, northern Italy, to verify whether an area of low-level urbanization has a lower risk of occurrence of SE (as recently suggested), different clinical features and short-term prognosis than areas of hi...

journal_title：European journal of neurology

authors： Vignatelli L,Rinaldi R,Galeotti M,de Carolis P,D'Alessandro R

更新日期：2005-11-01 00:00:00

abstract：:We report a long-term outcome of motor function in a patient with adult-onset adrenoleukodystrophy after bone marrow transplantation (BMT). Clinically motor function gradually improved and became almost normal in 2 years after BMT. Serial transcranial magnetic stimulation showed gradual improvement of central motor co...

journal_title：European journal of neurology

authors： Hitomi T,Mezaki T,Tomimoto H,Ikeda A,Shimohama S,Okazaki T,Uchiyama T,Shibasaki H

更新日期：2005-10-01 00:00:00

abstract：:The purpose of this study was to investigate the surface electromyogram (EMG) of the lower limbs of hemiplegic children with spastic cerebral palsy during gait. The EMG of seven muscles was analyzed for 17 children (5-12 years old). The EMG of the involved side was decreased for the examined shank muscles and increase...

journal_title：European journal of neurology

authors： Patikas D,Wolf S,Döderlein L

更新日期：2005-09-01 00:00:00

abstract：:We describe a case of cardiac myxoma whose clinical presentation mimicked that of polyarteritis nodosa. The serum levels of MPO-ANCA and IL-6 were elevated on laboratory investigation and normalized after the removal of the tumor. We suggest that a 'true' vasculitic mechanism contributes to the pathogenesis of pseudov...

journal_title：European journal of neurology

authors： Nishio Y,Ito Y,Iguchi Y,Sato H

更新日期：2005-08-01 00:00:00

abstract：:The majority of patients with multiple sclerosis (MS) experience gradual progression of disability, either as secondary progressive MS (SPMS) or primary progressive MS (PPMS). A subgroup with relapsing-remitting MS shows a benign course with little or no disease progression and minimal disability decades after the fir...

journal_title：European journal of neurology

authors： Ramsaransing GS,Heersema DJ,De Keyser J

更新日期：2005-07-01 00:00:00

abstract：:To study the efficacy and safety of tolperisone - a centrally acting muscle relaxant with membrane stabilizing activity - in the treatment of stroke-related spasticity. This was a randomized, double-blind, placebo-controlled, multicenter study with parallel groups. Treatment lasted 12 weeks and was started with a titr...

journal_title：European journal of neurology

authors： Stamenova P,Koytchev R,Kuhn K,Hansen C,Horvath F,Ramm S,Pongratz D

更新日期：2005-06-01 00:00:00

abstract：:In a previous, controlled study we demonstrated that the general lower limb activity measured by three-channel actometry is a promising objective measure of restless legs syndrome (RLS) severity. In the present study we have further evaluated the method in measuring RLS symptom severity in an open, single-day pramipex...

journal_title：European journal of neurology

authors： Tuisku K,Holi MM,Wahlbeck K,Ahlgren AJ,Lauerma H

更新日期：2005-05-01 00:00:00

abstract：:Population-based epidemiological studies on epilepsy are available mainly from the UK and the Nordic, Baltic and western Mediterranean countries. No studies were identified from large areas of Europe, especially from the former eastern Europe (except the Baltic countries) and the eastern Mediterranean countries. Based...

journal_title：European journal of neurology

authors： Forsgren L,Beghi E,Oun A,Sillanpää M

更新日期：2005-04-01 00:00:00

abstract：:Astasia, inability to stand unsupported despite good strength, resembles the marked balance impairment of patients with vestibulocerebellar disease. We describe a patient with unilateral thalamic infarct that presented with astasia. A 76-year-old hypertensive woman was admitted to our hospital because of marked unstea...

journal_title：European journal of neurology

authors： Lee PH,Lee JH,Joo US

更新日期：2005-04-01 00:00:00

abstract：:The incidence of the neuropathological lesions and the severity of the clinical symptoms in multiple sclerosis (MS) are correlated with the amount of the transferred autoreactive T cells. The balance between the T helper 1 (Th1) and T helper 2 (Th2) cytokine phenotypes may affect the activity of the disease in MS pati...

journal_title：European journal of neurology

authors： Ersoy E,Kuş CN,Sener U,Coker I,Zorlu Y

更新日期：2005-03-01 00:00:00

abstract：:Patients with mild cognitive impairment (MCI) typically present with memory complaints. Some of these patients have subcortical vascular disease on computed tomography (CT) scan, namely white matter changes and lacunar infarcts, however it is not known whether these findings are associated with more pronounced cogniti...

journal_title：European journal of neurology

authors： de Mendonça A,Ribeiro F,Guerreiro M,Palma T,Garcia C

更新日期：2005-02-01 00:00:00

abstract：:This study examined the relative anti-Parkinson's disease (PD) tremor potencies of pergolide and pramipexole in people with PD, using a 3-month double-blind cross-over design. Patients were randomly assigned to receive either pergolide and then pramipexole (n=9) or vice versa (n=8). The dose of the respective dopamine...

journal_title：European journal of neurology

authors： Navan P,Findley LJ,Undy MB,Pearce RK,Bain PG

更新日期：2005-01-01 00:00:00

abstract：:Most patients with acute disseminated encephalomyelitis (ADEM) recover quickly under corticosteroid treatment and have a favourable long-term prognosis. We report on a young woman with acute onset of an extensive and solitary white-matter lesion in the left hemisphere. Fever, high pleocytosis and elevated protein in c...

journal_title：European journal of neurology

authors： Harloff A,Rauer S,Hofer M,Klisch J,Els T

更新日期：2005-01-01 00:00:00

abstract：:Population-based data on the incidence, aetiology, and mortality associated with status epilepticus (SE) are required to develop preventative strategies for SE. Through a systematic review, we aimed to assess the methodological quality as well as similarities, and differences between available population based studies...

journal_title：European journal of neurology

authors： Chin RF,Neville BG,Scott RC

更新日期：2004-12-01 00:00:00

abstract：:Digital subtraction angiography (DSA) is considered to be the 'gold standard' for confirmation of severe (70-99%) stenoses of internal carotid arteries (ICAs). However, it is associated with a risk of complications. The aim of this study was to assess the accuracy of ultrasonography (US), computed tomographic angiogra...

journal_title：European journal of neurology

authors： Herzig R,Burval S,Krupka B,Vlachová I,Urbánek K,Mares J

更新日期：2004-11-01 00:00:00

abstract：:In this report, we present the clinical and pathological details of a kindred of four individuals with a novel missense mutation (V272A) of the presenilin 1 gene (PSEN1) that experienced a subcortical dementia. The age of onset of symptoms ranged 26-36-year old, with an age at death of 36-46 years. Initial symptom was...

journal_title：European journal of neurology

authors： Jimenez-Escrig A,Rabano A,Guerrero C,Simon J,Barquero MS,Güell I,Ginestal RC,Montero T,Orensanz L

更新日期：2004-10-01 00:00:00